Fluorosulphuric acid

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

key study

Study period:

4 days

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Cross-reference

Reason / purpose for cross-reference:

reference to same study

Data source

Reference

Reference Type:

publication

Title:

Acute Toxicity to Freshwater Benthic Macroinvertebrates of Fluoride ion (F-) in Soft Water

Author:

Camargo JA & Tarazona, JV

Year:

1990

Bibliographic source:

Bull. Environ. Contam. Toxicol. (1990), 45, 883-887.

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: US Environmental Protection Agency, 440/5-86-001; Method for Acute Toxicity Tests with Fish, Macroinvertebrates and Amphibians.

Principles of method if other than guideline:

No further information

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

Sodium fluoride

EC Number:

231-667-8

EC Name:

Sodium fluoride

Cas Number:

7681-49-4

Molecular formula:

NaF

IUPAC Name:

sodium fluoride

Details on test material:

All reported tests with aquatic organisms are performed with NaF because HF occurs in the aquatic environment mainly as fluoride ion so the NaF tests can therefore be used for the evaluation of HF effects in aquatic organisms.

Specific details on test material used for the study:

Sodium fluoride is water soluble and will rapidly dissociate under the aqueous conditions of the test to form sodium and fluoride ions. The toxicity of sodium fluoride is essentially due to fluoride ions and therefore is appropriate for read-across to HF.

Sampling and analysis

Analytical monitoring:

yes

Details on sampling:

No details on sampling given.

Test solutions

Vehicle:

no

Test organisms

Test organisms (species):

other: trichoptera aquatic larvae

Details on test organisms:

Trichoptera aquatic larvae were collected from fluoride unpolluted areas of Spanish rivers: Chimarra marginata Linnaeus, Hydropsyche lobata MacLachlan and Hydropsyche bulbifera MacLachlan from Rio Aulencia (Madrid), Hydropsyche exocellata Dufour from Rio Jarama (Madrid) and Hydropsyche pellucidula Curtis from Rio Duraton (Segovia).

Study design

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

96 h

Post exposure observation period:

No post exposure observation period.

Test conditions

Hardness:

12-19 mg CaCO3/L

Nominal and measured concentrations:

Measured

Details on test conditions:

Laboratory bioassays were performed in a glass aquaria each containing 10 L of dechlorinated tap water. Necessary water oxygenation and turbulence were produced by an air pump per aquarium. Chamber environmental temperature and natural photoperiod were utilised. Test fluroide solutions were made from sodium fluoride.

Reference substance (positive control):

not specified

Results and discussion

Effect concentrations

Duration:

96 h

Dose descriptor:

EC50

Effect conc.:

>= 26 - <= 48 mg/L

Nominal / measured:

meas. (not specified)

Conc. based on:

other: fluoride

Details on results:

Benthic larvae were very sensitive to the concentration of fluoride ion with EC50 values ranging from 26 to 48 mg/L (actual concentration).

Results with reference substance (positive control):

Not applicable.

Reported statistics and error estimates:

No reported statistics or estimations.

Any other information on results incl. tables

Benthic larvae were found to be sensitive to the concentration of fluoride ion with EC50 values ranging from 26 to 48 mg/L (actual concentration). These organisms appear more sensitive than D. magna according to the EU RAR for hydrogen fluoride; however this may be a reflection of the fact that the study was performed with soft water.

Applicant's summary and conclusion

Validity criteria fulfilled:

not applicable

Conclusions:

Benthic larvae were very sensitive to the concentration of fluoride ion with EC50 values ranging from 26 to 48 mg/L (actual concentration).

Executive summary:

Benthic larvae (Chimarra marginata, Hydropsyche lobata, Hydropsyche bulbifera, Hydropsyche exocellata and Hydropsyche pellucidula) collected in Spanish rivers were found to be sensitive to the concentration of fluoride ion with EC50 values ranging from 26 to 48 mg/L (actual concentration). These organisms appear more sensitive than D. magna according to the EU RAR for hydrogen fluoride; however this may be a reflection of the fact that the study was performed with soft water.