Fluorosulphuric acid

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:

toxicity to aquatic algae and cyanobacteria

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: see "reamrk"

Remarks:

Peer reviewed study, but missing a lot of documentation.

Justification for type of information:

Peer reviewed study, but missing a lot of documentation. However, due to the very low toxicity of sodium sulfate in all ecotoxicological endpoints and the comparable reference substance data, data from this study may be used with care. Previous expert opinion has also recognised the limitations of the study but permitted its use see below for iuclid 4 / SIDS rationale. Iuclid 4 Rationale: In this test a different algae species is used than recommended in the OECD-guidelines. When the results of Potassium dichromate (72 h, EbC50) used as a reference substance, are compared with the results given in the EC-directive 92/69/EEC (mean 0.53 mg/l, range 0.20 - 0.75 mg/l) the sensitivity of Nitzschia linearis is not significantly different from that of Selenastrum capricornutum or Scenedesmus subspicatus. It is recognised that the duration of this study was greater than the recommended OECD study time but as the reference result from this study is on the lower boundary of the EC recommendation, the two results are considered comparable. This study would be considered as validity 3 because of the shortcomings. However, based on the other data, Sodium sulfate is a substance of very low toxicity and the results of this study confirm this, therefore this study is evaluated as valid with restrictions (2).

Data source

Reference

Reference Type:

publication

Title:

The relative sensitivity of diatoms, snails, and fish to twenty common constituents of industrial wastes.

Author:

Patrick, R.J., Cairns, J., Scheier, A.

Year:

1968

Bibliographic source:

Fish-Cult. 30(3):137-140

Materials and methods

Test guideline

Qualifier:

according to guideline

Principles of method if other than guideline:

Pre-Guideline study was intended to look at variation between different species for common industrial wastes.

GLP compliance:

no

Remarks:

not applicable: pre-GLP

Test material

Test material information

Constituent 1

Reference substance name:

Sodium sulphate

EC Number:

231-820-9

EC Name:

Sodium sulphate

Cas Number:

7757-82-6

Molecular formula:

H2O4S.2Na

IUPAC Name:

disodium sulfate

Details on test material:

No specific information on the test material was given. All chemicals were of American Chemical Society grade.
Sodium Sulfate

Sampling and analysis

Analytical monitoring:

no

Test organisms

Test organisms (species):

other: Nitzschia linearis

Study design

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

120 h

Remarks on exposure duration:

Static

Results and discussion

Effect concentrations

Duration:

120 h

Dose descriptor:

EC50

Effect conc.:

1 900 mg/L

Any other information on results incl. tables

- Nominal/measured concentrations: nominal
- Effect data/Element values: growth (cell counts)
- Cell density data: not described
- Growth curves: not described
- Reference substance: Potassium dichromate, TLm = 0.208 mg/l

Applicant's summary and conclusion

Validity criteria fulfilled:

no

Conclusions:

This result shows that Sodium sulfate is not a substance of concern for diatoms. The reference test data are comparable to that of data for OECD
approved algae species. The response of the tested diatom species is therefore likely to be similar to approved test species. The data may therefore be used with care.