Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Toxicity to reproduction: other studies

Additional information

·        TIMES Androgen and Estrogen Binding Affinityv.03modelsare used;

·        The modelsarefocused on the direct interactions of chemicals with the androgenand estrogenreceptors(ARand ER) - that is, ARand ERbinding mediated endocrine disruptions. These interactionsareconsidered as primary eventsthat trigger the ultimate biological responses;

2-Propenenitrile, reaction products with 1,3-benzenedimethanamineincluding constituents MXDA, A, B, C and D is predicted asnot capableof eliciting interaction with androgen or estrogen receptors

Justification for classification or non-classification

Not classified as toxicity to reproduction.

Additional information