Registration Dossier
Registration Dossier
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EC number: 251-068-5 | CAS number: 32503-27-8
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
Additional information
No data is available regarding acute toxicity of tetrabutylammonium hydrogen sulphate.
A low acute toxicity for tetrabutylammonium hydrogen sulphate was expected based on read-across data with another salt of the same substance, tetrabutylammonium bromide CAS 1643-19-2. From public information on ECHA website related to registration dossier of tetrabutylammonium bromide CAS 1643-19-2 LD50 oral rat is 500 mg/kg/bw (experimental study of 2014 according to OECD 423).
The public ECHA database contains data that are proprietary and cannot be used without the formal consent of the owner. In this summary, some of them have been used for precautionary purposes and for the benefit of the human health and the environment. Those data are not necessary for the registration of the target substance which is used exclusively as isolated and transported intermediate, but they can be very helpful for a better definition of the (eco) toxicological property of the substance. No other use and no commercial advantage will derive from the use of those data.
Justification for classification or non-classification
According to the CLP Regulation (EC n. 1272/2008), the classification H302 (acute oral toxicity, cat.4) is proposed for tetrabutylammonium hydrogen sulphate. No data is available regarding acute toxicity of TBHS but there is some concern regarding this substance: tetrabutylammonium hydrogen sulphate is corrosive (see IUCLID section 7.3) and from ECHA website an analogous of TBHS (that is tetrabutylammonium bromide CAS 1643-19-2, another salt of the same substance) is classified H302.
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