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Physical & Chemical properties

Particle size distribution (Granulometry)

Administrative data

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2016
Report date:
2016

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: US Pharmacopeia 786, Ph.Eur 2.9.38
GLP compliance:
no
Type of method:
sieving
Type of distribution:
mass based distribution

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(1H-indol-3yl)ethanamine
EC Number:
692-120-0
Cas Number:
124955-50-6
Molecular formula:
C10H12N2*H3PO4
IUPAC Name:
2-(1H-indol-3yl)ethanamine
Test material form:
solid: crystalline
Details on test material:
Test item: tryptamine phosphateCAS No.:124955-50-6Batch No.: S62233NPhysical state: brown or beige crystalline powderStorage: 8-15 °C, protected from light and wet

Results and discussion

Particle sizeopen allclose all
Percentile:
D10
Mean:
0.095 mm
Remarks on result:
other: mean of three replicates
Percentile:
D50
Mean:
0.264 mm
Remarks on result:
other: mean of three replicates
Percentile:
D90
Mean:
0.454 mm
Remarks on result:
other: mean of three replicates
Particle size distribution at different passages
Remarks on result:
not determinable

Applicant's summary and conclusion