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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
results derived from a (Q)SAR model, with limited documentation / justification
Justification for type of information:
QSAR prediction

Data source

Reference
Reference Type:
other: Predicted data
Title:
Unnamed
Year:
2016

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: REACH guidance on QSARs R.6, May/July2008
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(1H-indol-3yl)ethanamine
EC Number:
692-120-0
Cas Number:
124955-50-6
Molecular formula:
C10H12N2*H3PO4
IUPAC Name:
2-(1H-indol-3yl)ethanamine
Test material form:
solid: crystalline
Details on test material:
Test item: tryptamine phosphateCAS No.:124955-50-6Batch No.: S62233NPhysical state: brown or beige crystalline powderStorage: 8-15 °C, protected from light and wet

Results and discussion

Effect concentrations
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
59.1 mg/L
Nominal / measured:
estimated
Remarks on result:
other: Database: Aquatic Japan MoE (Daphnia Magna)

Applicant's summary and conclusion

Conclusions:
According to (Q)SAR modell: QSAR Toolbox, the predicted value indicated that tryptamine phosphate is hazardous to the aquatic invertebrates (Daphnia magna). The result meets the requirement of Aquatic Acute Category 3.