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Ecotoxicological information

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Aquatic toxicity studies are available for the trophic levels fish, invertebrates, algae and aquatic microorganisms. In the acute toxicity test with fish (Danio rerio) and daphnia a saturated solution of 1 mL/L has been tested, which has been generated in a slow stirring procedure according to the OECD Guidance Document No 23 (2000) due to the low water solubility of the substance. The acute tests showed no effects at the limit of water solubility for Daphnia magna (EL50 >1 mg/L) and for fish (LC50 (96 h) >0.0383 mg/L (geom. mean))). The substance showed also no inhibitory effects on the growth rate of green algae at the limit of water solubility in a test according to OECD guideline TG 201. The EC50 (72 h) has been determined to be >0.037 mg/L based on the geometric mean and the NOEC was 0.037mg/L in the limit test. Nevertheless, no inhibitory effects rate have been observed in the study. A chronic reproduction study with Daphnia magna according to guideline OECD TG211 showed no significant effects on parental daphnia generation mortalities, no impairment of reproduction and no reduction of parental daphnia generation body length at the highest attainable test concentration under experimental conditions. The EC50 (21 days) for immobilization of the parental daphnia and the 21-day EC50 for reproduction and the corresponding NOEC have been estimated to be greater than 0.019 mg/L based on the geometric mean.

A respiration inhibition test with activated sludge (OECD TG 209), demonstrated that the substance caused no inhibiting effects on activated sludge of a municipal sewage treatment plant at the limit test substance concentration of 1000 mg/L and the NOEC (3 h) has been derived to be >= 1000 mg/L.

Overall, the test results demonstrate that the test substance reveals no toxicity to aquatic organisms at the limit of water solubility.