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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
12-16 May, 2003
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: A modern GLP study conducted according the appropriate guidelines.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2003
Report date:
2003

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
Linalyl propionate
EC Number:
205-627-5
EC Name:
Linalyl propionate
Cas Number:
144-39-8
Molecular formula:
C13H22O2
IUPAC Name:
linalyl propionate
impurity 1
Reference substance name:
Unknown impurities
Molecular formula:
not applicable
IUPAC Name:
Unknown impurities
Test material form:
liquid
Details on test material:
- Name of test material (as cited in study report): Linalyl Propionate
- Molecular formula: C13H22O2
- Molecular weight: 210.3 g/mol
- Physical state: colourless liquid
- Analytical purity: 97.3%
- Lot/batch No.: 9000470955
- Expiration date of the lot/batch: May 29, 2003

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
4.9
Temp.:
35 °C
pH:
7
Details on results:
Testing was performed at 35°C (column temperature), however the values can be considered to represent the values at an unspecified ambient temperature.

Any other information on results incl. tables

No further data

Applicant's summary and conclusion

Conclusions:
The partition coefficients n-octanol/water of Linalyl Propionate is log Pow = 4.9.
Executive summary:

The partition coefficient n-octanol/water of Linalyl Propionate was determined by the reverse HPLC method according to OECD guideline 117.

The partition coefficients n-octanol/water of Linalyl Propionate log Pow = 4.9.