Registration Dossier

Diss Factsheets

Administrative data

Description of key information

Not irritating according to a Draize-test with two rabbits (Hayashi et al., 1999, Toxicology in Vitro 13, 915-922)

Read-across data captured from published Benzophenone registration dossier:

Dermal rabbit (OECD Guideline 404): not irritating (study report 1999 Scantox, Lille Skensved, Denmark)

Dermal rabbit (Draize test): moderately irritating (Calas et al., 1977, Contact Dermatitis 3, 186-194)

Eye rabbit (Several crystals of the compound were placed into the conjunctival sac of 6 rabbit eyes (3 rinsed/not rinsed each)): slight eye irritation (Eastman Kodak Co., 1984)

Eye rabbit (Toxicity test for bulk chemicals to meet DOT regulations): not irritating, (Upjohn Co., 1984)

Key value for chemical safety assessment

Additional information

Justification for classification or non-classification

Classification, Labelling, and Packaging Regulation (EC) No 1272/2008

The available experimental test and read-across data is reliable and suitable for classification purposes under Regulation (EC) No 1272/2008, as amended for the seventh time in Regulation (EC) No 2015/1221. As a result the substance is considered to be not classified as corrosive or irritating to the eye and skin.