Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

QSAR prediction with OASIS TIMES: not sensitizing. The calculated value was out of domain (structural fragment) and is therefore only a hint (see the attachement for detailed information).

Read-across data captured from published Benzophenone registration dossier:

Skin guinea pigs (OECD Guideline 406): not sensitizing (Sharp et al., 1978, Toxicology 9, 261-271)

Skin guinea pigs (OECD Guideline 406): not sensitizing (Calas et al., 1977, Contact Dermatitis 3, 186-194)

Skin Maximization test in human volunteers: not sensitizing (Opdyke et al., 1979, Food Cosmet Toxicol 11, 873-874)

Key value for chemical safety assessment

Justification for classification or non-classification

Classification, Labelling, and Packaging Regulation (EC) No 1272/2008

The available read-across data is reliable and suitable for classification purposes under Regulation (EC) No 1272/2008, as amended for the seventh time in Regulation (EC) No 2015/1221. As a result the substance is considered to be not classified as sensitising to the skin.