Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study was performed accorrding to OECD protocols and GLP.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1995
Report date:
1995

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 402 (Acute Dermal Toxicity)
GLP compliance:
yes
Test type:
standard acute method
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
Fatty acids, C10-20-neo-
EC Number:
285-549-6
EC Name:
Fatty acids, C10-20-neo-
Cas Number:
85116-96-7
Molecular formula:
C10H20O2 ... C20H40O2
IUPAC Name:
C10-20-neo-Fatty acids
Details on test material:
brown liquid

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
male/female

Administration / exposure

Type of coverage:
occlusive
Vehicle:
unchanged (no vehicle)
Duration of exposure:
24 h
Doses:
2000 mg/kg
No. of animals per sex per dose:
5
Control animals:
no

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information
Conclusions:
Under the conditions of the study, the Median Dermal Dose (LD50) of Versatic 1019 in rats is considered to be greater than 2000 mg/kg.
Executive summary:

There were no premature decedents following a single dermally administered dose of 2000 mg/kg to one group of 5 male and 5 female rats.

Under the conditions of the study, the Median Dermal Dose (LD50) of Versatic 1019 in rats is considered to be greater than 2000 mg/kg.