Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Study period:
2014
Reliability:
4 (not assignable)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2014

Materials and methods

Principles of method if other than guideline:
QSAR (Toxtree)
Test type:
other: QSAR (Toxtree)

Test material

Constituent 1
Chemical structure
Reference substance name:
3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-2'-methyluridine
EC Number:
807-766-2
Cas Number:
863329-65-1
Molecular formula:
C24H21FN2O7
IUPAC Name:
3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-2'-methyluridine

Results and discussion

Any other information on results incl. tables

Based on QSAR results (Toxtree) and expert judgement, the substance is estimated to have an LD50 of 300 - 2000 mg/kg (oral, rat).

Applicant's summary and conclusion

Interpretation of results:
harmful
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
Classified as Acute toxicity cat 4 (oral) based on QSAR and expert judgement.