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EC number: 278-014-3 | CAS number: 74878-48-1
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- October from 27 to 30, 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- flask method
- Water solubility:
- 705.6 g/L
- Conc. based on:
- test mat.
- Incubation duration:
- 24 - 72 h
- Temp.:
- 20 °C
- Remarks on result:
- other: pH not specified
- Details on results:
- The recovery for the determination of test item in water was 99.5 %, indicating a sufficient accuracy of the analytical method.
PRELIMINARY ESTIMATION OF THE WATER SOLUBILITY
The preliminary visual experiments showed that the water solubility of the test item is between 500 g/l and 1000 g/l. - Conclusions:
- Water solubility: 705.6 g/l at 20 °C
- Executive summary:
The water solubility of the test item was investigated in a study conducted according to OECD Guideline 105 and EU Method A.6. Flask method was used for this purpose, while UV VIS-spectroscopy was used for the detection of the concentration of the test item. Based on the findings of the study, the water solubility of the test item at a temperature of 20 °C was determined to be 705.6 g/l.
Conclusion
Water solubility: 705.6 g/l at 20 °C
Reference
DETERMINATION OF THE SOLUBILITY IN THE WATER - FLASK METHOD
| Experiment | A | B | C | D (blank) |
| Amount of test item (mg) | 6000 | 6000 | 6000 | -- |
| Stirring time at 30 °C (h) | 24 | 48 | 72 | 72 |
| Measured concentration (mg/l) | 8.7 | 9.0 | 8.8 | -- |
| Dilution | 0.01 ml/10 ml 0.05 ml/4 ml |
0.01 ml/10 ml 0.05 ml/4 ml |
0.01 ml/10 ml 0.05 ml/4 ml |
-- |
| n-Octanol solubility (g/l) | 695.3 |
718.5 |
703.1 |
-- |
PRELIMINARY VISUAL ESTIMATION
Amount of the test item in mg |
Total volume in ml |
Appearance of mixture |
1000 |
1 |
undissolved |
1000 |
2 |
dissolved |
Appearance of the test mixtures
Description of key information
705.6 g/l at 20 °C
Key value for chemical safety assessment
- Water solubility:
- 705.6 g/L
- at the temperature of:
- 20 °C
Additional information
OECD Guidelines 105 - flask method
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