Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The key value for acute toxicity was derived from a study performed under GLP conditions and according to OECD 201. Pseudokirchnerella subcapitata was exposed to a single concentration of the test substance during 72 hours. The 72-h ErC10 and the 72-h ErC50 were determined to be 5.3 mg/L and 49 mg/L respectively.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 49 mg/L
- EC10 or NOEC for freshwater algae:
- 5.3 mg/L
Additional information
The acute toxicity of the substance to the green algae Pseudokirchnerella subcapitata was investigated in a 72 growth inhibition study (Vryenhoef, 2014) following the OECD 201 guideline. This study was considered as key study for the PNEC derivation (K-score is 1).
Analyses at 0 and 72 hours showed measured test concentrations to range from 94% to 117% of nominal values and so the results are based on nominal test concentrations only. The 72-h ErC50 and 72 -h ErC10 was set to 49 mg test substance/L and 5.3 mg test substance/L respectively.
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