Registration Dossier

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

EC50 Daphnia magna 48h for Sulfadimidine = 31.4 mg/l

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
31.4 mg/L

Additional information

Some data regarding short-term toxicity to aquatic invertebrates are reported in database ECOTOX, EPA for Sulfadimidine CAS 57-68-1:

- EC50 Daphnia magna 48h = values 31.4, 39, 109.5 and 185.3 base on different light source used (ref. Jung et all, Ecotoxicology 17(1): 37-45, 2008. Specific experimental condition are explained in the abstract free available on website : The lighting conditions were as follows: (1) fluorescent light only, (2) continuous irradiation with 15 microW/cm(2) UVB, (3) pulsed irradiation with 90 microW/cm(2) UVB for 4 h/d, and (4) natural sunlight (outdoors). Laboratory tests showed that phototoxicity resulting from exposure to continuous UVB light generally increased the acute toxicity of the sulfonamides in Daphnia magna.)

- EC50 Daphnia magna 48h = 174.4 mg/l (ref. Kim et all, Environ. Int.33(3): 370-375, 2007)

- EC50 Daphnia magna 48h = 202 mg/l (ref. De Liguoro, Chemosphere75(11): 1519-1524, 2009)

- EC50 Daphnia magna 48h = 215.9 mg/l (ref. Park et all, Ecotoxicology17(6): 526-538, 2008)


According to the CLP Regulation (EC n.1272/2008) the data of short-term toxicity to aquatic invertebrates for Sulfadimidine are of no concern for acute aquatic toxicity.