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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

Depending on local conditions and existing concentrations, disturbances in the biodegradation process of activated sludge are possible. The nitrification performance of activated sludge during the elimination via sewage treatment plants may be interfered.

Key value for chemical safety assessment

Additional information

In a GLP short-term respiration test according to OECD 209 conducted with 1,4-Dimethyl-1H-pyrazole (CAS 1072-68-0) an EC10 (180 min) of 1.1 mg/L (3h EC50 = 10 mg/L) was obtained for nitrification inhibition (3h values of 1.9 mg/L (EC10) and 110 mg/L (EC50) were determined for total oxygen uptake). The test was performed using domestic activated sludge.

The 3h EC10 value for nitrification inhibition (1.1 mg/L) was used for the derivation of the PNEC-STP.