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EC number: 600-813-6 | CAS number: 1072-68-0
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Depending on local conditions and existing concentrations, disturbances in the biodegradation process of activated sludge are possible. The nitrification performance of activated sludge during the elimination via sewage treatment plants may be interfered.
Key value for chemical safety assessment
Additional information
In a GLP short-term respiration test according to OECD 209 conducted with 1,4-Dimethyl-1H-pyrazole (CAS 1072-68-0) an EC10 (180 min) of 1.1 mg/L (3h EC50 = 10 mg/L) was obtained for nitrification inhibition (3h values of 1.9 mg/L (EC10) and 110 mg/L (EC50) were determined for total oxygen uptake). The test was performed using domestic activated sludge.
The 3h EC10 value for nitrification inhibition (1.1 mg/L) was used for the derivation of the PNEC-STP.
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