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Environmental fate & pathways

Adsorption / desorption

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Description of key information

Log Koc = 2.85 (HPLC-method, OECD 121)

Key value for chemical safety assessment

Additional information

The adsorption coefficient on soil and sewage sludge was estimated in a study by Brinkmann (2014). The study was conducted according to GLP and followed OECD guideline 121. The study was performed using a HPLC with a cyanopropyl chemical bound resin on a silica base column. Seven reference items with different retention times were used to produce a calibration curve. A solvent blank followed by three injections of a solution of the reference items were analysed with HPLC, then three injections of a solution of the test substance, and finally three injections of the solution with the reference items. For each reference item, the capacity factor k’ was calculated from the retention time of sodium nitrate and the retention time of the respective reference item. A calibration function was set up using the literature values for Koc of the reference items and the mean capacity factor of the six determinations. In the graph log k’ versus log Koc, linear regression was performed, giving r2 = 0.9771. The chromatogram of the test item gave one peak (mean RT = 4.614 min). With the help of the calibration, the Log Koc could be determined as 2.850 ± 0.003 (mean ± sd).