17,18-dihydrodinaphtho[1',2',3':3,4;3'',2'',1'':9,10]perylo[1,12-efg][1,4]dioxocin-5,10-dione

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

May 15, 2015 - July 17, 2015

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: guideline study (EC A.6. and OECD 105)

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

GLP compliance:

no

Type of method:

flask method

Water solubility:

< 1 other: mg (TOC) /L

Temp.:

20 °C

pH:

6

 Individual results

 

Preliminary visual estimation of the water solubility

Different amounts of the test item were stirred in 100 mL or 500 mL distilled water and the mixtures were visually checked for any undissolved parts.Table2 shows the results from the preliminary test.

 

Table2: Appearance of the test mixtures

Amount of test item in mg		Total volume in mL		Appearance of mixture
17.8		100		undissolved^1)
10.6		500		undissolved^1)
3.5		500		undissolved^1)

¹⁾: After adding the indicated amount of water, the solution was stirred for approx. 72 h.

The preliminary visual experiments showed that the solubility of the test item in water is below 7 mg/L (without correction for the purity). As the test item is insoluble in organic solvents it is impossible to coat the sea sand of the columns with the test item. For this reason, the column elution method is not applicable and the water solubility had to be determined by the flask method.

Results of the flask method

After the equilibration time, precipitate was observed in the flasks of the test item-treated samples.The water solubility was calculated from the measured and unrounded concentration values and not from the rounded values given in Table3.

Table3: Solubility of the test item in water- experiments

Experiment	24 h experiment	48 h experiment	72 h experiment	Blank experiment (72 h)
Amount of test item (mg)	8.1	8.5	9.3	--
Amount of distilled water (mL)	200	200	200	200
Stirring time at 30 °C (h)	24	48	72	72
pH at 23°C	6.0	6.0	6.1	5.9
Measured TOC concentration (mg C/L)	< 1	< 1	< 1	< 1

 

The TOC concentration in the aqueous samples was determined to be < 1 mg/l TOC.

Executive summary:

The water solubility c_S of the test item was determined at a temperature of 20 °C according to OECD 105. As the test item is not soluble in aqueous or organic solvents, it was not possible to analytically quantify Vat Black 16. Hence, the dissolved total organic carbon content (TOC) was measured.                                                                

It was determined to be:: < 1 mg (TOC) / L.

Description of key information

The water solubility of the test item was determined by the flask method according to the European Commission Regulations (EC) No. 440/2008 and No. 260/2014, A.6. Water solubility; flask method and according to the OECD test guideline, OECD 105 Water solubility.

Additional information

The water solubility was found to be below the quantification limit of 1 mg/l TOC.