Registration Dossier

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Study following official guidelines, GLP compliant performed on a mixture containing the substance and other analogue substances
Qualifier:
according to guideline
Guideline:
OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
Deviations:
yes
Remarks:
14 days observation
GLP compliance:
yes (incl. QA statement)
Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, domestic (adaptation not specified)
Details on inoculum:
Mixture of polyvalent bacteria collected November 11,1993 in the aeration tank of a domestic sewage treatment plant, ARABasel CommunalBacteria concentration : 30 mg TS/I
Duration of test (contact time):
ca. 14 d
Initial conc.:
ca. 100 mg/L
Based on:
test mat.
Parameter followed for biodegradation estimation:
O2 consumption
Details on study design:
Water/Nutrient: as specified in the methodTemperature: 20 +/- 2°CTest duration: 14 daysLighting: none
Reference substance:
benzoic acid, sodium salt
Parameter:
% degradation (O2 consumption)
Value:
ca. 0
Sampling time:
48 h
Details on results:
BOD / ThOD = 0%
Interpretation of results:
under test conditions no biodegradation observed
Conclusions:
The test item was tested for ready biodegradation following OECD 301C. Under the test conditions the test item is not ready biodegradable.
Executive summary:

The ready biodegradability of the test item was determined in a 14 days MITI - Test (I) according to the OECD Guideline for Testing of Chemicals, No. 301C, Paris 1981 and the EEC-Directive, 79/831, Annex V, C.7. The test substance was tested in a concentration of 100 mg/l. The reference substance Natriumbenzoat was also tested in a concentration of 100 mg/l. Under the experimental conditions the test substance is not readily biodegradable.

Description of key information

not readily or inherently biodegradable

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed

Additional information

The read-across substance was tested for ready biodegradation following OECD 301C. The read-across substance was tested for inherent biodegradation following OECD 302C Zahn Wellens test. Under the experimental conditions the test item is neither inherently nor readily biodegradable.

Based on the read-across considerations the same results apply to Acid Black 220.