Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
other: peer reviewed literature information
Adequacy of study:
other information
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
secondary source
Title:
Unnamed

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
2-ethylhexan-1-ol
EC Number:
203-234-3
EC Name:
2-ethylhexan-1-ol
Cas Number:
104-76-7
Molecular formula:
C8H18O
IUPAC Name:
2-ethylhexan-1-ol
Test material form:
other: liquid
Details on test material:
- Name of test material (as cited in study report): 2-Ethylhexanol

Test animals

Species:
rat
Strain:
not specified

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
not specified
Details on oral exposure:
single dosage
Doses:
5, 6, 8, 10, 12, 15 g/kg
No. of animals per sex per dose:
49 animals in total.
No. of animals per dose group not exatly specified
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
7 000 mg/kg bw
Based on:
not specified
Gross pathology:
cogestion of the spleen and liver
paleness of the kidney

Applicant's summary and conclusion