Registration Dossier
Registration Dossier
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EC number: 255-464-9 | CAS number: 41621-49-2
Oxidising properties
Administrative data
- Endpoint:
- oxidising solids
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2016
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The study is not GLP and does not follow the OECD Guideline.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
- Report date:
- 2016
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.17 (Oxidising Properties (Solids))
- GLP compliance:
- no
Test material
- Reference substance name:
- 6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
- EC Number:
- 255-464-9
- EC Name:
- 6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
- Cas Number:
- 41621-49-2
- Molecular formula:
- C12H17NO2.C2H7NO
- IUPAC Name:
- 6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
- Test material form:
- solid: particulate/powder
Constituent 1
Results and discussion
Test results (Oxidising solids)open allclose all
- Sample tested:
- other: 70:30 sample-to-cellulose ratio
- Parameter:
- burning rate
- Result:
- 90 s
- Sample tested:
- 1:1 sample-to-cellulose ratio
- Parameter:
- burning rate
- Result:
- 60 s
- Sample tested:
- other: 30:70 sample-to-cellulose ratio
- Parameter:
- burning rate
- Result:
- 60 s
- Sample tested:
- other: 10:90 sample-to-cellulose ratio
- Parameter:
- burning rate
- Result:
- 330 s
Any other information on results incl. tables
The sample was used as it is without any grinding or any other manipulation.
Cellulose was dried in an oven at 105° at ambient pressure for 16 hrs.
The ignition source was a flame from a gas burner.
A preliminary test was performed. Since the cone generated a vigorous reaction, the train test was carried out.
Several mistures of the prduct and cellulose were prepared (see table). The product burns with a vigorous flame emitting a black smoke.
| Product % w/w | Cellulose % w/w | Burning rate 20 cm in | Complete combustion (external) |
| 70 | 30 | 90'' | 180'' |
| 50 | 50 | 60'' | 180'' |
| 30 | 70 | 60'' | 150'' |
| 10 | 90 | 330'' | 390'' |
A blank was performed by mixing 50% of Ba(NO3)2 and 50% of cellulose: the burning rate of this mixture is much slower than that of Cyclopirox olamine hence cyclopirox olamine must be considered an oxidizing substance.
Applicant's summary and conclusion
- Interpretation of results:
- Category 1 (strong oxidising solids) based on GHS criteria
- Conclusions:
- Ciclopirox olamine is considered as oxidizing.
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