Registration Dossier
Registration Dossier
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EC number: 255-464-9 | CAS number: 41621-49-2
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1977
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- publication
- Title:
- Study of Medical Supplies
- Author:
- Iyakuhin Kenkyu
- Year:
- 1 977
- Bibliographic source:
- Study of Medical Supplies. Vol. 8, Pg. 107, 1977.
Materials and methods
- Principles of method if other than guideline:
- Data published. No detailed information about principles of method are available.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
- EC Number:
- 255-464-9
- EC Name:
- 6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
- Cas Number:
- 41621-49-2
- Molecular formula:
- C12H17NO2.C2H7NO
- IUPAC Name:
- 6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
- Test material form:
- solid: particulate/powder
Constituent 1
Test animals
- Species:
- rat
Administration / exposure
- Route of administration:
- oral: unspecified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 2 350 mg/kg bw
- Based on:
- not specified
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- LD50 oral (rat) for Ciclopirox Olamine is 2350 mg/kg bw
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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