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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Eye irritation

Currently viewing:

Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
other: read across based on OECD Toolbox v3.4
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
see attached OECD Toolbox study

Data source

Reference
Title:
No information
Author:
Anonymous
Year:
2016
Bibliographic source:
OECD Toolbox v3.4.0.17

Materials and methods

Test guideline
Guideline:
OECD Guideline 405 (Acute Eye Irritation / Corrosion)
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2-dimethyl-1,3-dioxane-4,6-dione
EC Number:
217-992-8
EC Name:
2,2-dimethyl-1,3-dioxane-4,6-dione
Cas Number:
2033-24-1
Molecular formula:
C6H8O4
IUPAC Name:
2,2-dimethyl-1,3-dioxane-4,6-dione
Test material form:
solid: particulate/powder

Test animals / tissue source

Species:
rabbit
Strain:
not specified

Results and discussion

In vivo

Results
Irritation parameter:
other: no data
Basis:
mean
Score:
0
Max. score:
110
Reversibility:
fully reversible
Remarks on result:
other: not irritating

Applicant's summary and conclusion

Interpretation of results:
not irritating