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Ecotoxicological information

Toxicity to microorganisms

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Endpoint:
toxicity to microorganisms, other
Remarks:
growth inhibition P. fluorescens and E. coli
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
July 1977
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
abstract
Qualifier:
no guideline available
Principles of method if other than guideline:
Not reported
GLP compliance:
no
Analytical monitoring:
no
Vehicle:
no
Test organisms (species):
Pseudomonas fluorescens
Test type:
static
Water media type:
freshwater
Limit test:
yes
Nominal and measured concentrations:
10 g/L
Reference substance (positive control):
no
Duration:
3 h
Dose descriptor:
EC10
Effect conc.:
> 10 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth inhibition
Validity criteria fulfilled:
not applicable
Conclusions:
The 3h-ErC10 for P. fluorescens and E. coli were determined to be >10000 mg/L.
Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
July 1977
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
abstract
Qualifier:
no guideline available
Principles of method if other than guideline:
Not reported
GLP compliance:
no
Analytical monitoring:
no
Vehicle:
no
Test organisms (species):
activated sludge
Test type:
static
Water media type:
freshwater
Limit test:
yes
Nominal and measured concentrations:
100 mg/L
Reference substance (positive control):
no
Duration:
3 h
Dose descriptor:
IC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration
Validity criteria fulfilled:
not applicable
Conclusions:
The 3h-IC10 for activated sludge was determined to be >100 mg/L.
Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
July 1982
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
abstract
Qualifier:
no guideline available
Principles of method if other than guideline:
Not reported
GLP compliance:
no
Analytical monitoring:
no
Vehicle:
no
Test organisms (species):
activated sludge
Test type:
static
Water media type:
freshwater
Limit test:
yes
Nominal and measured concentrations:
100 mg/L
Reference substance (positive control):
no
Duration:
3 h
Dose descriptor:
IC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration
Validity criteria fulfilled:
not applicable
Conclusions:
The 3h-IC10 for activated sludge was determined to be >100 mg/L.
Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
November 1982
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
abstract
Qualifier:
no guideline available
Principles of method if other than guideline:
Not reported
GLP compliance:
no
Analytical monitoring:
no
Vehicle:
no
Test organisms (species):
activated sludge
Test type:
static
Water media type:
freshwater
Limit test:
yes
Nominal and measured concentrations:
100 mg/L
Reference substance (positive control):
no
Duration:
3 h
Dose descriptor:
IC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration
Validity criteria fulfilled:
not applicable
Conclusions:
The 3h-IC10 for activated sludge was determined to be >100 mg/L.
Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
Mai 1983
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
abstract
Qualifier:
no guideline available
Principles of method if other than guideline:
Not reported
GLP compliance:
no
Analytical monitoring:
no
Vehicle:
no
Test organisms (species):
activated sludge
Test type:
static
Water media type:
freshwater
Limit test:
yes
Nominal and measured concentrations:
100 mg/L
Reference substance (positive control):
no
Duration:
3 h
Dose descriptor:
IC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration
Validity criteria fulfilled:
not applicable
Conclusions:
The 3h-IC10 for activated sludge was determined to be >100 mg/L.

Description of key information

Based on a weight-of-evidence approach the IC50 (respiration inhibtion) to bacteria is >100 mg/L.

Key value for chemical safety assessment

EC50 for microorganisms:
100 mg/L

Additional information