Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Hazard for air

Hazard for terrestrial organisms

Hazard for predators

Additional information

Conclusion on classification

 

Environmental classification and labelling of a substance is generally based on data from short-term aquatic toxicity results, the ready biodegradability of the substance and an experimentally determined BCF (or if absent the measured octanol/water partition coefficient). Available adequate chronic toxicity data is also relevant for the assessment of long-term aquatic hazards (Regulation 286/2011/EC).

 

Short-term aquatic toxicity data is available for 2 trophic levels (daphnia and algae). Based on valid studies the determined EC50 values are respectively, for Daphnia and algae, 11.09 and 15.4 mg/L. Since all EC50s are > 1mg/L the substance is not classified for short-term (acute) hazards to the aquatic environment according to the CLP Regulation 1272/2008/EC.

 

Chronic aquatic toxicity data is only available for one trophic level (algae). Therefore, the long-term (chronic) hazard has been assessed based on both:

a) The chronic aquatic toxicity data for algae (NOEC = 1.43 mg/L) which results in no chronic classification (> 1mg/L, not rapidly biodegradable), and

b) The acute aquatic toxicity data for daphnia (EC50 = 11.09 mg/l) and environmental fate data (not readily biodegradable and log Kow of >4.0), which results in a chronic classification Cat 3 and therefore classifies Givescone according to the most stringent outcome.

 

Thus it is concluded that the substance is classified for long-term (chronic) aquatic cat 3 (H412) hazard according to the CLP Regulation 1272/2008/EC & adaptation 286/2011/EC.

 

According to the old DSD regulation, Directive 67/548/EEC, the substance would be classified as R52/53 for environmental hazards.