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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2015-10-28 to 2015-10-29
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: OECD Test Guideline 113 (1981): Screening Test for Thermal Stability and Stability in Air
Deviations:
no
Qualifier:
equivalent or similar to guideline
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Version / remarks:
1996, applies to result
Deviations:
no
GLP compliance:
no
Remarks:
The study was conducted under supervision of a quality assurance unit which had ensured e.g instrumentation validation, reagent/materials certification, analyst certification and providing standard operating procedures.
Type of method:
dynamic method
Key result
Temp.:
20 °C
Vapour pressure:
0.73 hPa
Key result
Temp.:
25 °C
Vapour pressure:
0.95 hPa
Key result
Temp.:
50 °C
Vapour pressure:
3.2 hPa
Test no.:
#1
Temp.:
94.8 °C
Vapour pressure:
19.5 hPa
Test no.:
#2
Temp.:
118.8 °C
Vapour pressure:
39.7 hPa
Test no.:
#3
Temp.:
126.8 °C
Vapour pressure:
49.5 hPa
Test no.:
#4
Temp.:
134.7 °C
Vapour pressure:
62 hPa
Test no.:
#5
Temp.:
140.5 °C
Vapour pressure:
78.5 hPa
Test no.:
#6
Temp.:
146.1 °C
Vapour pressure:
93.5 hPa
Test no.:
#7
Temp.:
136.9 °C
Vapour pressure:
68.9 hPa
Test no.:
#8
Temp.:
129.5 °C
Vapour pressure:
55 hPa
Test no.:
#9
Temp.:
114.5 °C
Vapour pressure:
34.9 hPa

Pre test: Thermal Stability

The test item in a closed glass crucible showed a small exothermic effect in the temperature range of 120 - 170 °C, with an energy of – 10 J/g.

 

Main test: Dynamic method - Vapour-liquid equilibrium (VLE)

The vapour pressure was measured in the temperature range of 94.8 to 146.1 °C. 

From the measured data points of the vapour pressure curve the constants A, B and C of the Antoine equation was derived by regression (Microsoft Excel) of the data points to

 

A = 8.7920

B = -2031.68

C = 273.15

 

The vapour pressure of the test item was calculated by extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C, according to Regulation (EC) No 440/2008 Method A.4.

Conclusions:
The vapour pressure of the test substance was determined to be 0.73 hPa at 20 °C, 0.95 hPa at 25 °C and 3.20 hPa at 50 °C.
Executive summary:

A study was conducted according to OECD TG 104 determine the vapour pressure of the test item using the dynamic method (VLE). A vapour pressure curve with 9 data points was measured over a temperature range between 94.8 to 146.1 °C. From the measured data points of the vapour pressure curve the constants A, B and C of the Antoine equation was derived and the vapour pressure of the test item as calculated by extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C, according to Regulation (EC) No 440/2008 Method A.4. The vapour pressure of the test substance was determined to be 0.73 hPa at 20 °C, 0.95 hPa at 25 °C and 3.20 hPa at 50 °C.

Description of key information

The vapour pressure of the test substance was determined to be 0.73 hPa at 20 °C, 0.95 hPa at 25 °C and 3.20 hPa at 50 °C.

Key value for chemical safety assessment

Vapour pressure:
0.73 hPa
at the temperature of:
20 °C

Additional information

A study was conducted according to OECD TG 104 to determine the vapour pressure of the test item using the dynamic method (VLE). A vapour pressure curve with 9 data points was measured over a temperature range between 94.8 to 146.1 °C. The vapour pressure of the test item was calculated by extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C. The vapour pressure of the test substance was determined to be 0.73 hPa at 20 °C, 0.95 hPa at 25 °C and 3.20 hPa at 50 °C.