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Diss Factsheets
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EC number: 203-397-0 | CAS number: 106-43-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
The acute toxicity of 4 -chlorotoluene towards fish was determined in a 14d assay. The EC50 accounts for 5.92 mg/L (Koenemann, 1979).
Testing 4-chlorotoluene in an Early-Life Stage Toxicity Test with a method similar to the OECD guideline 210, a NOEC (28d) of 1.9 mg/l was observed (Van Leeuwen 1990).
The acute toxicity of 4-chlorotoluene towards daphnids is characterized by an EC50(48h) of 1.7 mg/L (Rose 1997).
The long-term toxicity of 4-chlorotoluene towards daphnids is characterized by a NOEC(21 d) of 0.32 mg/L as well as an EC50(21 d) of 1.6 mg/L referring to the reproduction of the test animals (Nite 1999).
For the algae Selenastrum capricornutum (new name: Pseudokirchnerella subcapitata) a 72 h NOEC of 2.2 mg/l as well as EC50 of 6.1 mg/L was determined. The determination was performed following the OECD Guideline 201. (Nite 1999)
The toxicity of 4 -chlorotoluene towards microorgansims was tested by the means of Pseudomonas putida growth inhibition yielding an EC10(18 h) of > 25 mg/L (Trenel 1982).
The toxicity of 4 -chlorotoluene towards microorganisms was investigated by the means of the lethal response of Spirostomum ambiguum yielding a LC50(48 h) of 110.8 mg/L (Nalecz-Jawecki, 2002).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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