Registration Dossier
Registration Dossier
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EC number: 606-278-5 | CAS number: 19257-34-2
Dissociation constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- dissociation constant
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 2002
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Guideline:
- other: other guideline: Estimation Program "ACD/pKa DB" (Advanced Chemistry Development Inc., Toronto, Canada)'
- GLP compliance:
- no
- Dissociating properties:
- no
- Conclusions:
- The chemical structure of the substance does not show any groups, which can be protonated or deprotonated.
Therefore, the substance can be considered as a neutral molecule in the pH range 2 - 10, which is of relevance for biological systems. - Executive summary:
The substance does not contain any functional group which can be protonated or deprotonated significantly in aqueous solution.
With the computer program ACD/pKa DB (Advanced Chemistry Development Inc., Toronto, Canada) a pKa value could not be calculated.
Therefore, the substance is to be considered a neutral molecule in the pH range 2 - 10, which is of relevance for aqueous biological systems.
Reference
The chemical structure of the substance does not show any groups, which can be protonated or deprotonated.
Therefore, the substance can be considered as a neutral molecule in the pH range 2 - 10, which is of relevance for biological systems.
With the computer program ACD/pKa DB a pKa value could not be calculated.
Description of key information
The chemical structure of the substance does not show any groups, which can be protonated or deprotonated.
Therefore, the substance can be considered as a neutral molecule in the pH range 2 - 10, which is of relevance for biological systems.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
