Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2021
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 112 (Dissociation Constants in Water)
GLP compliance:
yes (incl. QA statement)
Dissociating properties:
no
Remarks on result:
not determinable because of methodological limitations
Conclusions:
The dissociation constant of the test item should be determined according to the European Commission Regulation (EC) No. 2017/735, A.25 and according to the OECD test guideline 112. Despite adding water miscible organic solvents the solubility of the test item was too low for the determination of dissociation constants.
Executive summary:

The dissociation constant of the test item should be determined according to the European Commission Regulation (EC) No. 2017/735, A.25 and according to the OECD test guideline 112. Despite adding water miscible organic solvents the solubility of the test item was too low for the determination of dissociation constants.

Description of key information

The dissociation constant of the test item should be determined according to the European Commission Regulation (EC) No. 2017/735, A.25 and according to the OECD test guideline 112. Despite adding water miscible organic solvents the solubility of the test item was too low for the determination of dissociation constants.

Key value for chemical safety assessment

Additional information