Isobutyrophenone

Short-term toxicity to fish

Administrative data

Endpoint:

short-term toxicity to fish

Type of information:

experimental study

Adequacy of study:

other information

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Non-GLP guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1989

Report date:

1989

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: DIN 38412 part 15

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

Isobutyrophenone

EC Number:

210-275-0

EC Name:

Isobutyrophenone

Cas Number:

611-70-1

Molecular formula:

C10H12O

IUPAC Name:

2-methyl-1-phenylpropan-1-one

Details on test material:

- Name of test material (as cited in study report): Darocur Stufe 1
- Physical state: clear, pale yellow liquid
- Analytical purity: 99.5%

Sampling and analysis

Analytical monitoring:

no

Test solutions

Vehicle:

no

Test organisms

Test organisms (species):

Leuciscus idus

Details on test organisms:

TEST ORGANISM
- Common name: Golden orfe
- Source: Zoo Meyer, Darmstadt, Germany
- Feeding during test: none

Study design

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

48 h

Test conditions

Test temperature:

20 °C

Nominal and measured concentrations:

Nominal test concentrations: 20, 30, 40, 50, 75 mg/L

Details on test conditions:

TEST SYSTEM
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 1

TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: synthetic test water according to DIN 38412 part 15

OTHER TEST CONDITIONS
- Illumination: daylight

EFFECT PARAMETERS MEASURED: mortality after 48 hours

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

48 h

Dose descriptor:

LC0

Effect conc.:

30 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Effect concentrations 2

Duration:

48 h

Dose descriptor:

LC50

Effect conc.:

36 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Effect concentrations 3

Duration:

48 h

Dose descriptor:

LC100

Effect conc.:

75 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality (fish)