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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
OECD107

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
GLP compliance:
no
Type of method:
flask method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
1-(methylamino)anthraquinone
EC Number:
201-417-2
EC Name:
1-(methylamino)anthraquinone
Cas Number:
82-38-2
Molecular formula:
C15H11NO2
IUPAC Name:
1-(methylamino)anthraquinone
Test material form:
solid
Specific details on test material used for the study:
Purity: 98,5 % (w/w)

Study design

Analytical method:
liquid chromatography

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
4.95
Temp.:
23 °C
pH:
ca. 8.2
Details on results:
A saturated stock solution of the test substance in water saturated n-octanol was prepared.
To 5 ml, 10 ml and 20 ml of the filtered stock solution 10 ml of n-octanol saturated water were added. The two-phase system was shaken vigorously at room temperature (23 °C) for one hour. After phase separation the test substance concentration in each phase was determined by HPLC.
Stock solution: 948 mg/l = 934 mg/l active substance.

Applicant's summary and conclusion

Conclusions:
The test substance has a log Pow of 4.95 at 23°C.
Executive summary:

The log Pow of the test substance was determined according OECD107. The log Pow at 23 °C is 4.95.

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