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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: screening tests
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Report date:
2015

Materials and methods

Principles of method if other than guideline:
The ready biodegradability was estimated by using BIOWIN, Toxtree and Vega predictors.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-chloro-4-[1-(oxan-2-yl)-1H-pyrazol-5-yl]benzonitrile
EC Number:
941-996-5
Cas Number:
1297537-35-9
Molecular formula:
C15H14N3ClO
IUPAC Name:
2-chloro-4-[1-(oxan-2-yl)-1H-pyrazol-5-yl]benzonitrile

Results and discussion

Applicant's summary and conclusion

Interpretation of results:
other: NOT ready biodegradable.
Conclusions:
In the consensus assessment only reliable predictions are to be taken into account. In this case, 2-chloro-4-(1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-yl)benzonitrile was predicted as not ready biodegradable by BIOWIN (moderate reliable) and as not ready biodegradable by Toxtree (reliability assessment not applicable). Thus, based on BIOWIN/Toxtree predictions it was concluded that 2-chloro-4-(1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-yl)benzonitrile can be moderately reliably predicted as NOT ready biodegradable.