Registration Dossier
Registration Dossier
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EC number: 249-050-7 | CAS number: 28479-22-3
Endpoint summary
Administrative data
Description of key information
acute oral toxicity: LD50 > 6100 mg/kg bw for rat
acute inhalative toxicity: LC50 = 71 mg/L air (guideline study)
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- discriminating dose
- Value:
- 6 100 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Dose descriptor:
- LC50
- Value:
- 71 mg/m³ air
Additional information
A single oral application per gavage of 5 ml/kg bw (ca. 6100 mg/kg bw) of substance on 5 male and 5 female rats no deaths occured. The LD50 is therefore > 6100 mg/kg bw for rats.
In a guideline study according OECD 403 for male rats a LC50 = 110 mg/m³ air and for female rats a LC50 = 71 mg/m³ air was found.
For acute dermal toxicty no data were found.
Justification for classification or non-classification
For the acute oral toxicity a classification is not justified as a result of the LD50 > 6100 mg/kg bw
For the acute inhalation toxicity T+, R26 is justified as a result of the LC50 = 113 mg/m³ air
In addition, respiration irritational effects were reported. Therefore R 37 is applicable
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