Registration Dossier
Registration Dossier
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EC number: 943-688-6 | CAS number: -
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- other: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- 13-08-1991
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- See section 13
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test)
- Deviations:
- no
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, domestic, non-adapted
- Details on inoculum:
- Sludge of a domestic sewage treatment plant (ARA-Rhein) collected on 14 August 1990Sludge concentration: 1000 mg/l
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 100 mg/L
- Based on:
- DOC
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- Water / Nutrient: according to the specification of the EEC L133 (pp. 99-105) Volume 31 resp. OECD Method 302B.Temperature: 22.0 ± 3°C Lighting: indirect daylightTwo tests are running in parallel
- Reference substance:
- diethylene glycol
- Key result
- Parameter:
- other: bioelimination
- Value:
- 33.5
- Sampling time:
- 28 d
- Remarks on result:
- other: Adsorption after 3 hours: 33.4 %
- Details on results:
- The result is an average of two tests running in parallel. Adsorption after 3 hours: 33.4 %.
Results with refernce substance: 99.6 % after 12 days - Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- Bioelimination after 28 days was 33.5 % where the adsorption after 3 hours was 33.4 %.
The substance is considered to be non readily biodegradable. - Executive summary:
Biodegradation test was carried out according to OECD guideline 302B. The bioelimination value was 33.5 % (average of two tests running in parallel) after 28 days, where the adsorption after 3 hours was 33.4 %.
Reference
Description of key information
Not readily biodegradable
Key value for chemical safety assessment
Additional information
The probability of rapid biodegradation of the test substance has been calculated by QSAR Dyes R&C prediction tools. The overall assessment is based on the responses given by different predictive models for biodegradability under various conditions. The substance was predicted to be not ready biodegradable.
Moreover, being the substance a dye, it is not intended to be readily biodegradable, by the nature of its design and use.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
