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Environmental fate & pathways

Biodegradation in water: screening tests

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Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
other: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Study period:
13-08-1991
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
See section 13
Qualifier:
according to guideline
Guideline:
OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test)
Deviations:
no
GLP compliance:
yes
Oxygen conditions:
aerobic
Inoculum or test system:
sewage, domestic, non-adapted
Details on inoculum:
Sludge of a domestic sewage treatment plant (ARA-Rhein) collected on 14 August 1990Sludge concentration: 1000 mg/l
Duration of test (contact time):
28 d
Initial conc.:
100 mg/L
Based on:
DOC
Parameter followed for biodegradation estimation:
DOC removal
Details on study design:
Water / Nutrient: according to the specification of the EEC L133 (pp. 99-105) Volume 31 resp. OECD Method 302B.Temperature: 22.0 ± 3°C Lighting: indirect daylightTwo tests are running in parallel
Reference substance:
diethylene glycol
Key result
Parameter:
other: bioelimination
Value:
33.5
Sampling time:
28 d
Remarks on result:
other: Adsorption after 3 hours: 33.4 %
Details on results:
The result is an average of two tests running in parallel. Adsorption after 3 hours: 33.4 %.
Results with refernce substance: 99.6 % after 12 days
Validity criteria fulfilled:
yes
Interpretation of results:
not readily biodegradable
Conclusions:
Bioelimination after 28 days was 33.5 % where the adsorption after 3 hours was 33.4 %.
The substance is considered to be non readily biodegradable.
Executive summary:

Biodegradation test was carried out according to OECD guideline 302B. The bioelimination value was 33.5 % (average of two tests running in parallel) after 28 days, where the adsorption after 3 hours was 33.4 %.

Description of key information

Not readily biodegradable

Key value for chemical safety assessment

Additional information

The probability of rapid biodegradation of the test substance has been calculated by QSAR Dyes R&C prediction tools. The overall assessment is based on the responses given by different predictive models for biodegradability under various conditions. The substance was predicted to be not ready biodegradable.


Moreover, being the substance a dye, it is not intended to be readily biodegradable, by the nature of its design and use.