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Boiling point

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Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017-01-31 – 2017-01-31
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
Experimental result performed using standard methods of analysis
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling point/boiling range)
Principles of method if other than guideline:
The boiling point of a liquid is the temperature at which that liquid is converted to a gaseous state. It can be defined as the temperature at which the vapour pressure of the liquid becomes equal to the pressure at the surface of the liquid.
GLP compliance:
no
Type of method:
method according to Siwoloboff
Specific details on test material used for the study:
- Name of the test material: 3',6'-bis(diethylamino)spiro[isobenzofuran-1(3H),9'-
[9H]xanthene]-3-one
- Molecular formula: C28H30N2O3
- Molecular weight: 442.556 g/mol
- Substance type: Organic
- Smiles: C12(c3c(Oc4c1ccc(c4)N(CC)CC)cc(N(CC)CC)cc3)c1c(cccc1)C(O2)=O
Key result
Boiling pt.:
> 340 °C
Atm. press.:
978.4 hPa
Remarks on result:
other: no other details available

Method Details

Observations

Remarks if, any

Guideline

OECD 103

 

Method

Method according to

Siwoloboff

 

Principle of Boiling

point test

A sample is heated gradually in a tube which is immersed in a liquid bath.

The sample tube is held in

close contact with a thermometer and it contains a boiling capillary which is

fused about1 cm above its lower end. Upon approach of the boiling temperature bubbles emerge rapidly

from the lower open end of

the capillary. The boiling temperature is that temperature at which, on

momentary cooling, the string of bubbles stops and liquid suddenly rises in the capillary.

The substance melts and forms sticky texture ,without producing string of bubbles and rise in capillary upto 340°C, inferring b.p.

to be greater than 340°C.

Quantity of

chemical used

g/ml

1 ml

Nature of the Bath

taken

Oil bath

Water bath

OIL

 

If oil bath is used, specify

Liquid paraffin

Silicone oil

SILICON

Atmospheric

pressure

hPa

978.4

mean Boiling

point (°C)

(RESULT)

°C

greater than 340

Conclusions:
The boiling point determination of 3',6'-bis(diethylamino)spiro[isobenzofuran-1(3H),9'- [9H]xanthene]-3-one (CAS No. 509-34-2) was done following OECD Guideline 103 and according to the method of Siwoloboff. The substance melts and forms sticky texture ,without producing string of bubbles and rise in capillary upto 340°C, inferring b.p. to be greater than 340°C at 978.4 hPa.
Executive summary:

The boiling point determination of 3',6'-bis(diethylamino)spiro[isobenzofuran-1(3H),9'- [9H]xanthene]-3-one (CAS No. 509-34-2) was done following OECD Guideline 103 and according to the method of Siwoloboff. The substance  melts and forms sticky texture ,without producing string of bubbles and rise in capillary upto 340°C, inferring b.p. to be greater than 340°C at 978.4 hPa.

Description of key information

The boiling point determination of 3',6'-bis(diethylamino)spiro[isobenzofuran-1(3H),9'- [9H]xanthene]-3-one (CAS No. 509-34-2) was done following OECD Guideline 103 and according to the method of Siwoloboff. The substance  melts and forms sticky texture ,without producing string of bubbles and rise in capillary upto 340°C, inferring b.p. to be greater than 340°C at 978.4 hPa.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
340 °C

Additional information

The boiling point determination of 3',6'-bis(diethylamino)spiro[isobenzofuran-1(3H),9'- [9H]xanthene]-3-one (CAS No. 509-34-2) was done following OECD Guideline 103 and according to the method of Siwoloboff. The substance  melts and forms sticky texture ,without producing string of bubbles and rise in capillary upto 340°C, inferring b.p. to be greater than 340°C at 978.4 hPa.

Other supporting study from authoritative database suggests that the boiling point of chemical 3',6'-bis(diethylamino)spiro[isobenzofuran-1(3H),9'- [9H]xanthene]-3-one is reported to be 637.2±55.0 °C at  760 Torr pressure.

As the data from lab has K1 reliability and the test was performed using OECD guidelines which has the value of boiling point as greater than 340 degree C at 978.4 hPa,thus considered as key study for the chemical safety assessment