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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

 The LD50 in female rats was found to be greater than 2000 mg/kg body weight.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
2 000 mg/kg bw

Additional information

The median lethal dose of Cyclohexylphenylketone after single oral administration to female rats, observed over a period of 14 days is LD50(female rat): greater than 2000 mg/kg body weight. At the dose applied, one out of six female rats died.

Justification for classification or non-classification

There are conclusive but not sufficient data for classification of Cyclohexylphenylketone with regard to acute toxicity.

Cyclohexylphenylketone is not classified for this endpoint in accordance to Directive 67/548/EEC or the CLP Regulation (EC) No 1272/2008

However, since mortality occurred in 1/6 rats, class V classification will apply for GHS.