Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

not irritating to skin and no serious eye damage

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

Cyclohexylphenylketone was reported to cause minimal irritation when applied to intact and abraded rabbit skin. Out of a maximum of 8, the primary irritation index was 0.4.

No irritation effects were observed in the in-vitro HET-CAM test.

Effect level: empty Endpoint conclusion: Adverse effect observed

Justification for classification or non-classification

There are conclusive but not sufficient data for classification of Cyclohexylphenylketone with regard to skin irritation.

Cyclohexylphenylketone is not classified for this endpoint in accordance to Directive 67/548/EEC or the CLP Regulation (EC) No 1272/2008.

The in-vitro eye irritation test (HET-CAM) does not allow for classification of eye irritation and is limited to discriminate substances causing serious eye damage from substances that do not have that potential.