Registration Dossier

Diss Factsheets

Administrative data

Description of key information

not irritating to skin and no serious eye damage

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

Cyclohexylphenylketone was reported to cause minimal irritation when applied to intact and abraded rabbit skin. Out of a maximum of 8, the primary irritation index was 0.4.

No irritation effects were observed in the in-vitro HET-CAM test.

Effect level: empty Endpoint conclusion: Adverse effect observed

Justification for classification or non-classification

There are conclusive but not sufficient data for classification of Cyclohexylphenylketone with regard to skin irritation.

Cyclohexylphenylketone is not classified for this endpoint in accordance to Directive 67/548/EEC or the CLP Regulation (EC) No 1272/2008.

The in-vitro eye irritation test (HET-CAM) does not allow for classification of eye irritation and is limited to discriminate substances causing serious eye damage from substances that do not have that potential.