Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
sub-chronic toxicity: oral
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Title:
No information
Author:
Anonymous
Year:
2010
Bibliographic source:
OECD Toolbox v2.0, November 2010

Materials and methods

Test guideline
Guideline:
other: read across
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzoin
EC Number:
204-331-3
EC Name:
Benzoin
Cas Number:
119-53-9
Molecular formula:
C14H12O2
IUPAC Name:
2-hydroxy-1,2-diphenylethanone

Test animals

Species:
rat
Sex:
male/female

Administration / exposure

Route of administration:
oral: feed
Duration of treatment / exposure:
45d

Results and discussion

Effect levels

Dose descriptor:
NOEL
Effect level:
30.3 mg/kg bw/day (nominal)
Based on:
test mat.
Sex:
male/female
Basis for effect level:
other: 45d test; undefined organ, undefined effect

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion