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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Link to relevant study record(s)

Reference
Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Study period:
no data
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
The study was performed according to a valid guideline without any deviations and was conducted under GLP conditions. Furthermore, the data were submitted by another legal entity, under Directive 67/548/EEC, at least 12 years previously. The registrant has been granted permission to use the information, which has been extracted from the ECHA databases, for REACH registration purposes. No full information related to the experimental result are available but these deficiencies do not affect the quality of the relevant results.
Qualifier:
according to guideline
Guideline:
EU Method C.3 (Algal Inhibition test)
Version / remarks:
92/69/EEC
Deviations:
not specified
GLP compliance:
yes
Specific details on test material used for the study:
Details on properties of test surrogate or analogue material (migrated information):
no data
Analytical monitoring:
not specified
Details on sampling:
no data
Vehicle:
not specified
Details on test solutions:
ldentity and concentration of auxiliary solvent for dispersl: Culture medium
Test organisms (species):
Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
Details on test organisms:
no data
Test type:
not specified
Water media type:
not specified
Limit test:
yes
Total exposure duration:
72 h
Remarks on exposure duration:
no data
Post exposure observation period:
no data
Hardness:
Water hardness is not measured.
Test temperature:
no data
pH:
no data
Dissolved oxygen:
no data
Salinity:
no data
Conductivity:
no data
Nominal and measured concentrations:
Nominal concentration was 100 mg/L.
Details on test conditions:
no data
Reference substance (positive control):
not specified
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
> 0.71 mg/L
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
biomass
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
> 0.71 mg/L
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
growth rate
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
0.71 mg/L
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
growth rate
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
0.71 mg/L
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
biomass
Details on results:
no data
Results with reference substance (positive control):
no data
Reported statistics and error estimates:
no data

no data

Validity criteria fulfilled:
not specified
Conclusions:
ErC50 (0 to 72h) > 0.71 mg/L.
Executive summary:

An experimental study was performed under GLP contidions and according to EU Method C.3.

Under the test conditions, the EC50 (72 h) of the test material was determined to be > 0.71 mg/l.

There was no toxicity upon exposure to a nominal concentration of 100 mg/L of the test substance, and the NOEC can be considered as >100 mg/L (equal to 0.71 mg/l)

The result suggests that the test material is not toxic up to the limit of solubility.

Description of key information

  
    

perimental study was performed under GLP contidions and according to EU Method C.3.

An experimental study was performed under GLP contidions and according to EU Method C.3. Under the test conditions, the EC50 (72 h) of the test material was determined to be > 0.71 mg/l. There was no toxicity upon exposure to a nominal concentration of 100 mg/L of the test substance, and the NOEC can be considered as >100 mg/L (equal to 0.71 mg/l) The result suggests that the test material is not toxic up to the limit of solubility.

Under the test conditions, the EC50 (72 h) of the test material was determined to be > 0.71 mg/l.

There was no toxicity upon exposure to a nominal concentration of 100 mg/L of the test substance, and the NOEC can be considered as >100 mg/L (equal to 0.71 mg/l)

The result suggests that the test material is not toxic up to the limit of solubility.

An experimental study was performed under GLP contidions and according to EU Method C.3.

The EC50 (72 h) of the test material was determined to be > 0.71 mg/l.
There was no toxicity upon exposure to a nominal concentration of 100 mg/L of the test substance, and the NOEC can be considered as >100 mg/L (equal to 0.71 mg/l)
The result suggests that the test material is not toxic up to the limit of solubility

Key value for chemical safety assessment

EC50 for freshwater algae:
0.71 mg/L
EC10 or NOEC for freshwater algae:
0.71 mg/L

Additional information

no data

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