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Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
data is from experimental reports
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Principles of method if other than guideline:
The water solubility determination of test item N-potassium phthalimide (CAS No. 1074-82-4) was done as per the OECD guideline 105 and by spectrophotometric analytical method as per OECD 101.
GLP compliance:
not specified
Type of method:
flask method
Specific details on test material used for the study:
- Name of test material (as cited in study report): Phthalimide, potassium salt
- Molecular formula : C8H5NO2.K
- Molecular weight 185.223 g/mol
- Smiles notation : c12c(C(=O)[NH-]C1=O)cccc2.[K+]
- InChl: 1S/C8H5NO2.K/c10-7-5-3-1-2-4-6(5)8(11)9-7;/h1-4H,(H,9,10,11);/q;+1/p-1
- Substance type: Organic
- Physical state: Solid
Key result
Water solubility:
1 154.952 mg/L
Conc. based on:
test mat.
Temp.:
28 °C
Remarks on result:
other: no additional details mentioned

Sample Stirring time (hours)

Concentration obtained on the basis of standard curve

Dilution factor

Solubility value obtained (mg/l)

24

-

-

-

48

57.2600

20

1145.2

72

77.6456

15

1164.684

Considering the water solubility for 48 hrs and 72 hrs the mean water solubility was calculated as follows:

Mean water solubility value for 48 hour run sample + 72 hour run sample

=(1145.2+1164.684)/2

=1154.942 mg/L

Conclusions:
The water solubility determination of test item N-potassium phthalimide(CAS No.1074-82-4) was done by the spectrophotometric method.
The water solubility for the test item N-potassium phthalimide was determined to be 1154.942 mg/L at 28°C.
Executive summary:

The water solubility determination of test item N-potassium phthalimide (CAS No. 1074-82-4) was done as per the OECD guideline 105 and by spectrophotometric analytical method as per OECD 101. The solubility of N-potassium phthalimide (CAS:1074 -82-4 ) in water was determined to be 1154.942 mg/L at 28°C.

This value suggests that N-potassium phthalimide is soluble in water.

Description of key information

The water solubility determination of test item N-potassium phthalimide (CAS No. 1074-82-4) was done as per the OECD guideline 105 and by spectrophotometric analytical method as per OECD 101. The solubility of N-potassium phthalimide (CAS:1074 -82-4 ) in water was determined to be 1154.942 mg/L at 28°C.

This value suggests that N-potassium phthalimide is soluble in water.

Key value for chemical safety assessment

Water solubility:
1 154.942 mg/L
at the temperature of:
28 °C

Additional information

The water solubility determination of test item N-potassium phthalimide (CAS No. 1074-82-4) was done as per the OECD guideline 105 and by spectrophotometric analytical method as per OECD 101. The solubility of N-potassium phthalimide (CAS:1074 -82-4 ) in water was determined to be 1154.942 mg/L at 28°C.

The estimated water solubility of potassium phthalimide at 25 deg C was 1000000 mg/l.

The other supporting experimental and estimated values also suggest that N-potassium phthalimide is soluble in water.

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