N-potassium phthalimide

Biodegradation in water and sediment: simulation tests

Link to relevant study record(s)

Reference

Endpoint:

biodegradation in water: sediment simulation testing

Type of information:

calculation (if not (Q)SAR)

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

accepted calculation method

Justification for type of information:

Data is from computational model developed by USEPA

Qualifier:

according to guideline

Guideline:

other: Modeling database

Principles of method if other than guideline:

Fugacity Model by EPI Suite estimation database

GLP compliance:

not specified

Specific details on test material used for the study:

- Name of test material (as cited in study report): Potassium phthalimide
- Molecular formula (if other than submission substance): C8H5NO2.K
- Molecular weight (if other than submission substance): 185.223 g/mol
- Smiles notation (if other than submission substance): c12c(C(=O)[NH-]C1=O)cccc2.[K+]
- InChI: 1S/C8H5NO2.K/c10-7-5-3-1-2-4-6(5)8(11)9-7;/h1-4H,(H,9,10,11);/q;+1/p-1
- Substance type: Organic
- Physical state: solid

Radiolabelling:

not specified

Oxygen conditions:

other: estimation

Inoculum or test system:

not specified

Parameter followed for biodegradation estimation:

test mat. analysis

Compartment:

water

% Recovery:

19.1

Remarks on result:

other: Other details not known

Compartment:

sediment

% Recovery:

0.118

Remarks on result:

other: Other details not known

Key result

% Degr.:

50

Parameter:

other: Half-life in water

Sampling time:

15 d

Remarks on result:

other: Other details not known

Key result

% Degr.:

50

Parameter:

other: Half-life in sediment

Sampling time:

135 d

Remarks on result:

other: Other details not known

Key result

Compartment:

water

DT50:

15 d

Type:

other: estimated data

Temp.:

25 °C

Remarks on result:

other: Other details not known

Key result

Compartment:

sediment

DT50:

135 d

Type:

other: estimated data

Temp.:

25 °C

Remarks on result:

other: Other details not known

Transformation products:

not specified

	Mass Amount (percent)	Half-Life (hr)	Emissions (kg/hr)
Water	19.1	360	1000
Sediment	0.118	3.24e+003	0

 

	Fugacity (atm)	Reaction (kg/hr)	Advection (kg/hr)	Reaction (percent)	Advection (percent)
Water	4.46e-023	826	429	27.5	14.3
Sediment	3.82e-023	0.569	0.0532	0.019	0.00177

Validity criteria fulfilled:

not specified

Conclusions:

Estimated half life of Potassium phthalimide in water was 15 days (360 h) and in sediment estimated to be 135 days (3240 h).

Executive summary:

Estimation Programs Interface (EPI) Suite (2017) prediction model was run to predict the half-life in water and sediment for the test compound Potassium phthalimide (CAS No. 1074 -82 -4). If released in to the environment, 19.1% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of Potassium phthalimide in water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is moderate to low whereas the half-life period of Potassium phthalimide in sediment is estimated to be 135 days (3240 hrs). However, as the percentage release of test chemical into the sediment is less than 1% (i.e, reported as 0.118%), indicates that Potassium phthalimide is not persistent in nature.   

Description of key information

Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound Potassium phthalimide (CAS No. 1074 -82 -4). If released in to the environment, 19.1% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of Potassium phthalimide in water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is moderate to low whereas the half-life period of Potassium phthalimide in sediment is estimated to be 135 days (3240 hrs). However, as the percentage release of test chemical into the sediment is less than 1% (i.e, reported as 0.118%), indicates that Potassium phthalimide is not persistent in nature.   

Key value for chemical safety assessment

Half-life in freshwater:

15 d

at the temperature of:

25 °C

Half-life in freshwater sediment:

135 d

at the temperature of:

25 °C

Additional information

Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound Potassium phthalimide (CAS No. 1074 -82 -4). If released in to the environment, 19.1% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of Potassium phthalimide in water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is moderate to low whereas the half-life period of Potassium phthalimide in sediment is estimated to be 135 days (3240 hrs). However, as the percentage release of test chemical into the sediment is less than 1% (i.e, reported as 0.118%), indicates that Potassium phthalimide is not persistent in nature.