Registration Dossier
Registration Dossier
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EC number: 406-176-9 | CAS number: 79072-96-1 NC-4
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1991
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- not specified
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- Not available
- Analytical monitoring:
- yes
- Vehicle:
- no
- Details on test solutions:
- Nominal test solutions prepared at 0.3, 1.0, 3.0, 10.0, 30.0, 100.0 mg/L
- Test organisms (species):
- Daphnia magna
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Hardness:
- 231 mg/L as CaCO3
- Nominal and measured concentrations:
- Nominal concentrations: 0.3, 1.0, 3.0, 10.0, 30.0, 100.0 mg/L
Measured concentrations: <0.01, 0.01, 0.031. 0.039, 0.1, 0.343 mg/L - Reference substance (positive control):
- not specified
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 0.343 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The test material was determined to have a 48 hour EC50 >100 mg/l (nominal concentration) in an acute toxicity study on Daphnia magna. The 48 EC50 based on measured concentration is >0.343 mg/L
Reference
Description of key information
The test material was determined to have a 48 hour EC50 >100 mg/l (nominal concentration) in an acute toxicity study on Daphnia magna. The 48 EC50 based on measured concentration is >0.343 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.343 mg/L
Additional information
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