Registration Dossier
Registration Dossier
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EC number: 454-190-9 | CAS number: 324763-51-1
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low conditions.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 1 000 mg/L
Additional information
Considering the toxicity of propanamide, 3-amino-2,2-dimethyl- (CAS 324763 -51 -1) to microorganisms, experimental data from two studies are available. The key study is a GLP compliant OECD Guideline 209 study resulting in a 30-min EC EC50 value of >1,000 mg/L using domestic activated sludge as inoculum (BASF AG, 2005; no analytical monitoring performed). In a further supporting GLP compliant OECD 209 study (also performed without analytical monitoring), a 3-h EC50 value of 13,000 mg/L was observed with activated sludge from a domestic STP as inoculum (CETA, 2004).
The 30-min EC50 of >1,000 mg/L will be used for the assessment.
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