Registration Dossier
Registration Dossier
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EC number: 619-383-6 | CAS number: 98967-40-9
Endpoint summary
Administrative data
Description of key information
A dermal irritation study (Mizell MJ (1988a)) and an eye irritation study (Mizell MJ (1988b)) were conducted on Flumetsulam using rabbits.
There were no signs of dermal irritation in any of the rabbits at any time post-treatment.
Slight conjunctival redness, slight conjunctival chemosis and reddening of the iris were observed up to 24 hours post-instillation. There were no signs of ocular irritation in any of the animals at the 48 or 72 hours post-treatment observations. There were no signs of corneal opactiy at any time during the study.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
All studies were reliable EPA guideline studies performed to GLP standard. All were considered robust enough to be key.
Justification for classification or non-classification
With reference to the information available on this substance, no classification for irritation is required in accordance with Directive 67/548/EEC or Regulation (EC) No. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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