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Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
no data
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Insufficient documentation for an assessment of reliability.
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2000
Report date:
2000

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
3-(2-CHLOROETHYL)-9-HYDROXY-2-METHYL-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE HYDROCHLORIDE (1:1)
EC Number:
617-648-0
Cas Number:
849727-62-4
Molecular formula:
C11H11ClN2O2.HCl
IUPAC Name:
3-(2-CHLOROETHYL)-9-HYDROXY-2-METHYL-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE HYDROCHLORIDE (1:1)
Details on test material:
no data

Results and discussion

Solubility in organic solvents / fat solubilityopen allclose all
Medium:
methanol
Solubility:
78 g/L
Temp.:
20 °C
Medium:
ethanol
Solubility:
9.5 g/L
Temp.:
20 °C
Medium:
other: methylene chloride
Solubility:
1.3 g/L
Temp.:
20 °C
Medium:
other: acetone
Solubility:
0.84 g/L
Temp.:
20 °C
Medium:
other: isopropanol
Solubility:
1.7 g/L
Temp.:
20 °C
Medium:
other: dimethylformamide
Solubility:
14 g/L
Temp.:
20 °C

Any other information on results incl. tables

Table 1 Solubility of the T002006 at 20 deg C

 Solvent  Solubility in g/L solution
1-methoxy-2-propanol   2.8
 N,N-dimethylacetamide  23
 acetic acid  1.3

Applicant's summary and conclusion