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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

Currently viewing:

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
March 1974
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1974
Report date:
1974

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
10 animals were dosed with 5gm/kg of test substance and observed for 14 days
GLP compliance:
no
Test type:
fixed dose procedure
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
2,6-dimethylhept-5-enal
EC Number:
203-427-2
EC Name:
2,6-dimethylhept-5-enal
Cas Number:
106-72-9
Molecular formula:
C9H16O
IUPAC Name:
2,6-dimethylhept-5-enal
impurity 1
Chemical structure
Reference substance name:
6-methylhept-5-en-2-one
EC Number:
203-816-7
EC Name:
6-methylhept-5-en-2-one
Cas Number:
110-93-0
Molecular formula:
C8H14O
IUPAC Name:
6-methylhept-5-en-2-one
impurity 2
Chemical structure
Reference substance name:
(1R,2R,5R)-2-methyl-5-(prop-1-en-2-yl)cyclopentan-1-ol
Cas Number:
83059-39-6
Molecular formula:
C9H16O
IUPAC Name:
(1R,2R,5R)-2-methyl-5-(prop-1-en-2-yl)cyclopentan-1-ol
impurity 3
Chemical structure
Reference substance name:
(1R,2S,5R)-2-methyl-5-(prop-1-en-2-yl)cyclopentan-1-ol
Cas Number:
83026-65-7
Molecular formula:
C9H16O
IUPAC Name:
(1R,2S,5R)-2-methyl-5-(prop-1-en-2-yl)cyclopentan-1-ol
impurity 4
Reference substance name:
2-(3-methylcyclopent-2-en-1-yl)propan-2-ol
Molecular formula:
C9H16O
IUPAC Name:
2-(3-methylcyclopent-2-en-1-yl)propan-2-ol
Test material form:
liquid

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
not specified
Doses:
5000 mg/kg
No. of animals per sex per dose:
10 animals total
Control animals:
no
Details on study design:
Standard oral LD50 protocol at the time.

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 5 000 mg/kg bw
Mortality:
no deaths were seen in the 14 day observation period.
Clinical signs:
None
Body weight:
NA
Gross pathology:
NA

Any other information on results incl. tables

Distribution of Mortality

Observation Day
Route 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Oral 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
No toxicity was observed in the study at the limit of 5000 mg/kg bw
Executive summary:

10 animals were dosed with 5gm/kg of test substance and observed for 14 days. No toxicity was observed in the study at the limit of 5000 mg/kg bw.