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Short-term toxicity to fish

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Reference
Endpoint:
short-term toxicity to fish
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
weight of evidence
Justification for type of information:
Important considerations for the read-across were:
- calcium tartrate (the target chemical) has similar physico-chemical properties as the others members of the Category "Tartaric acids and its salts" (the source chemicals);
these properties include molecular weight; logKow and solubility
- there are structural similarities between all the chemicals of the Category.
Remarks on result:
not measured/tested
Sublethal observations / clinical signs:

LC50 values higher than 100 mg/L were predicted for tartaric acid by valid QSAR models.

Based on the assumption that in dilute aqueous conditions of defined pH, a salt will be fully dissociated and will behave no differently to the parent acid at identical concentration of the particular speciated form present, the aquatic toxicity of tartaric acid salts (i.e. monosodium, monopotassium, sodium potassium, sodium, potassium and calcium tartrate) may be assessed using data specific for tartaric acid. Therefore, also the tartaric acid salts are deemed to be non-toxic to fish.

Conclusions:
LC50 values higher than 100 mg/L were predicted for tartaric acid by valid QSAR models.
Executive summary:

LC50 values higher than 100 mg/L were predicted for tartaric acid by valid QSAR models.

Based on the assumption that in dilute aqueous conditions of defined pH, a salt will be fully dissociated and will behave no differently to the parent acid at identical concentration of the particular speciated form present, the aquatic toxicity of tartaric acid salts (i.e. monosodium, monopotassium, sodium potassium, sodium, potassium and calcium tartrate) may be assessed using data specific for tartaric acid. Therefore, also the tartaric acid salts are deemed to be non-toxic to fish.

Description of key information

Tartaric acid and its salts (e.g. Calcium tartrate) are not expected to be toxic to fish.

Key value for chemical safety assessment

Additional information

LC50 values higher than 100 mg/L were predicted for tartaric acid by valid QSAR models.

Based on the assumption that in dilute aqueous conditions of defined pH, a salt will be fully dissociated and will behave no differently to the parent acid at identical concentration of the particular speciated form present, the aquatic toxicity of tartaric acid salts (i.e. monosodium, monopotassium, sodium potassium, sodium, potassium and calcium tartrate) may be assessed using data specific for tartaric acid. Therefore, also the tartaric acid salts are deemed to be non-toxic to fish.