Registration Dossier
Registration Dossier
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EC number: 257-827-7 | CAS number: 52301-70-9
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1999
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- not specified
- GLP compliance:
- yes
- Analytical monitoring:
- not specified
- Details on sampling:
- None
- Vehicle:
- yes
- Details on test solutions:
- Control: 0 mg/L
Test (1000 mg/L): 1000 mg/L - Test organisms (species):
- Daphnia magna
- Test type:
- not specified
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
- Post exposure observation period:
- None
- Hardness:
- None
- Test temperature:
- 20 °C
- pH:
- 8.0 - 8.1
- Dissolved oxygen:
- 99 %
- Salinity:
- None
- Nominal and measured concentrations:
- Control: 0 mg/L
Test: 1000 mg/L - Details on test conditions:
- None
- Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- > 1 000 mg/L
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 1 000 mg/L
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- > 1 000 mg/L
- Details on results:
- For each control and test sample concentration 10 daphnids were included. The number of immobilized daphnids and % immobility noted to be 0.
- Results with reference substance (positive control):
- None
- Reported statistics and error estimates:
- None
- Validity criteria fulfilled:
- yes
- Conclusions:
- EC0: 1000 mg/L
EC50: >1000 mg/L
EC100: >1000 mg/L - Executive summary:
The acute toxicity of the substance to Daphnia magna was determined in a 48-hour static test according to the OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test). In the control and in all test concentrations no immobilization of the daphnids were observed after 48 hours. The EC50 values is greater than 1000 mg /L.
Reference
Immobilization of Daphnia: Number of immobilized Daphnia after 24 and 48 hours
| Nominal Conc. Of test material (mg/l) | No. of Daphnia tested | No. of immobilixzed Daphnia after: | % of immobilized Daphnia after: | ||
| 24 h | 48 h | 24 h | 48 h | ||
| Control | 5 | 0 | 0 | 0 | 0 |
| 5 | 0 | 0 | |||
| Solvent control | 5 | 0 | 0 | 0 | 0 |
| 5 | 0 | 0 | |||
Description of key information
The acute toxicity of the test item to Daphnia magna was determined in a 48-hour static test according to the OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test). Daphnids were exposed to the substance at 1000 mg/l. In the control and in all test concentrations no immobilization of the daphnids has been observed after 48 hours of substance exposure. The EC50 value therefore is set to be greater than 1000 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 1 000 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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