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EC number: 219-924-2 | CAS number: 2576-47-8
Endpoint summary
Administrative data
Description of key information
Appearance:
On the basis of physical observation done,the chemical 2-Bromoethylamine hydrobromide was observed to be colourless crystalline solid in appearance.
Melting point:
The melting point determination of 2-bromoethylammonium bromide (CAS No. 2576-47-8) was done following OECD Guideline 102 and according to the metal block capillary method. The test was conducted in replicates and Mean Melting temperature range was determined to be 168 °C-171°C at 979.2hPa.
Boiling point:
The boiling point determination of 2-bromoethylammonium bromide (CAS No. 2576-47-8) was done following OECD Guideline 103 and according to the method of Siwoloboff. The test was conducted in replicates and mean boiling point was determined to be 181.3°C at 979.2 hPa.
Density:
The density of substance 2-bromoethylammonium bromide (CAS No. 2576-47-8)was determined following OECD Guideline 109 and according to the Test methods: Pour density and tapped density of powders” recommended in The International Pharmacopoeia, Fourth Edition, 2014 using bulk density apparatus. The mean pour density and tapped density of test item was determined to be 0.9784 g/cm³ and 1.180 g/cm³at 28.3°C and 979.4 hPa.
Particle Size Distribution:
The particle size distribution of test item 2-bromoethylammonium bromide (CAS No. 2576-47-8 ) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 150 micron to 75 micron.
Vapor Pressure:
Data from authoritative databases suggests that the estimated vapor pressure of 2-bromoethanaminium bromide at 25 deg C was 0.00054 Pa.
Partition coefficient:
The partition Coefficient n-octanol/water of 2-bromoethylammonium bromide(CAS No.2576-47-8) was determined by the Reverse Phase High Performance Liquid Chromatographic method according to OECD Guideline No. 117 for testing of Chemicals. The reference substances were chosen according to estimated Pow range of the test substance and generalized calibration graph was prepared. The reference substances were having Pow value ranging from 0.5 to 4.9. TheLog Pow value was determined to be 0.7947 ± 0.0115 at 25°C.
Data from various authoritative databases suggests that the estimated logPow of 2-bromoethanaminium bromide was -2.99
These values suggest that 2 -bromoethylammonium bromide is hydrophillic in nature, which is also supported by its high solubility in water.
Water Solubility:
The water solubility determination of test item 2-bromoethylammonium bromide (CAS No. 2576-47-8) was done as per the OECD guideline 105 byspectrophotometric analytical method as per OECD 101. The solubility of 2-bromoethylammonium bromide (CAS: 2576-47-8) in water was determined to be 84020.07 mg/L at 28°C.
Data from authoritative databases suggests that the estimated solubility of 2-bromoethanaminium bromide in water at 25 deg C was 1000000 mg/l.
These values indicate that 2 -bromoethylammonium bromide can be considered to be highly soluble in water.
Surface tension:
Based on the data from ACD labs, surface tension for 2-bromoethanaminium bromide was predicted to be 36.6±3.0 dyne/cm.
Flash point:
The flash point determination of 2-bromoethylammonium bromide (CAS No. 2576-47-8)was done following closed cup method using Pensky-Martens flash point apparatus. The test was conducted in replicates and mean flash point was found to be 61.6°C at 979.3hPa. Based on criteria mentioned in CLP regulation the chemical has flash point >than 60 degree C hence the 2-bromoethylammonium bromide (CAS No. 2576-47-8) was considered to be non-flammable.
Autoflammability:
2-bromoethanaminium bromide did not catch fire on being exposed to air at room temperature of 27°C and atmospheric pressure of 966 hPa. This indicates that 2-bromoethanaminium bromide is not auto-flammable.
Flammability:
2-bromoethanaminium bromide does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 2-bromoethanaminium bromide is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 2-bromoethanaminium bromide was considered non-flammable for chemical safety assessment.
Explosivenss:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties
Oxidising properties:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidising properties and hence, the classification procedure does not need to be applied
pH:
The pH determination of test item 2-bromoethylammonium bromide (CAS No 2576-47-8) was done following OECD guideline 122. pH of 1% w/v solution was measured with the help of pH meter and it was observed to be 5.08 at 28 °C. Thus, 1% solution can be considered to be acidic in pH.
Viscosity:
The study does not need to be conducted because the substance is a solid
Additional information
Appearance:
On the basis of physical observation done,the chemical 2-Bromoethylamine hydrobromide was observed to be colourless crystalline solid in appearance.
other supporting studies from various authoritative databases also suggests that the chemical 2-Bromoethylamine hydrobromide was observed to be white coloured crystalline solid in appearance.
Melting point:
The melting point determination of 2-bromoethylammonium bromide (CAS No. 2576-47-8) was done following OECD Guideline 102 and according to the metal block capillary method. The test was conducted in replicates and Mean Melting temperature range was determined to be 168 °C-171°C at 979.2hPa.
Other supporting studies from various reliable sources such as authoritative database and handbook suggests that the melting point of chemical 2-Bromoethylamine hydrobromide was determined to be in the range of 168 degree C to 174 degree C
As the data from lab has K1 reliability and the test was performed using OECD guidelines which has the value of melting point as 168degree Cto 171 degree C at 979.2 hPa,thus considered as key study for the chemical safety assessment
Boiling point:
The boiling point determination of 2-bromoethylammonium bromide (CAS No. 2576-47-8) was done following OECD Guideline 103 and according to the method of Siwoloboff. The test was conducted in replicates and mean boiling point was determined to be 181.3°C at 979.2 hPa.
Density:
The density of substance 2-bromoethylammonium bromide (CAS No. 2576-47-8)was determined following OECD Guideline 109 and according to the Test methods: Pour density and tapped density of powders” recommended in The International Pharmacopoeia, Fourth Edition, 2014 using bulk density apparatus. The mean pour density and tapped density of test item was determined to be 0.9784 g/cm³ and 1.180 g/cm³at 28.3°C and 979.4 hPa.
Based on prediction done using ACD/I-Lab 2.0,the density of chemical 2-Bromoethylamine hydrobromide was estimated to be 1.581 ± 0.06 g/cm3.
As the data from lab has K1 reliability and the test was performed using OECD guidelines which has the value of mean pour density and tapped density as 0.9784 g/cm³ and 1.180 g/cm³at 28.3°C and 979.4 hpa,thus considered as key study for the chemical safety assessment
Particle Size Distribution:
The particle size distribution of test item 2-bromoethylammonium bromide (CAS No. 2576-47-8 ) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 150 micron to 75 micron.
Vapor Pressure:
Data from authoritative databases suggests that the estimated vapor pressure of 2-bromoethanaminium bromide at 25 deg C was 0.00054 Pa.
Partition coefficient:
The partition Coefficient n-octanol/water of 2-bromoethylammonium bromide(CAS No.2576-47-8) was determined by the Reverse Phase High Performance Liquid Chromatographic method according to OECD Guideline No. 117 for testing of Chemicals. The reference substances were chosen according to estimated Pow range of the test substance and generalized calibration graph was prepared. The reference substances were having Pow value ranging from 0.5 to 4.9. TheLog Pow value was determined to be 0.7947 ± 0.0115 at 25°C.
Data from various authoritative databases suggests that the estimated logPow of 2-bromoethanaminium bromide was -2.99
These values suggest that 2 -bromoethylammonium bromide is hydrophillic in nature, which is also supported by its high solubility in water.
Water Solubility:
The water solubility determination of test item 2-bromoethylammonium bromide (CAS No. 2576-47-8) was done as per the OECD guideline 105 byspectrophotometric analytical method as per OECD 101. The solubility of 2-bromoethylammonium bromide (CAS: 2576-47-8) in water was determined to be 84020.07 mg/L at 28°C.
Data from authoritative databases suggests that the estimated solubility of 2-bromoethanaminium bromide in water at 25 deg C was 1000000 mg/l.
These values indicate that 2 -bromoethylammonium bromide can be considered to be highly soluble in water.
Surface tension:
Based on the data from ACD labs, surface tension for 2-bromoethanaminium bromide was predicted to be 36.6±3.0 dyne/cm.
Flash point:
The flash point determination of 2-bromoethylammonium bromide (CAS No. 2576-47-8)was done following closed cup method using Pensky-Martens flash point apparatus. The test was conducted in replicates and mean flash point was found to be 61.6°C at 979.3hPa. Based on criteria mentioned in CLP regulation the chemical has flash point >than 60 degree C hence the 2-bromoethylammonium bromide (CAS No. 2576-47-8) was considered to be non-flammable.
Autoflammability:
2-bromoethanaminium bromide did not catch fire on being exposed to air at room temperature of 27°C and atmospheric pressure of 966 hPa. This indicates that 2-bromoethanaminium bromide is not auto-flammable.
Flammability:
2-bromoethanaminium bromide does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 2-bromoethanaminium bromide is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 2-bromoethanaminium bromide was considered non-flammable for chemical safety assessment.
Explosivenss:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties
Oxidising properties:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidising properties and hence, the classification procedure does not need to be applied
Viscosity:
The study does not need to be conducted because the substance is a solid
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