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Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1992
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Similar to guideline, according to GLP without analysis of test concentrations.
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 201 (Alga, Growth Inhibition Test)
GLP compliance:
yes
Analytical monitoring:
not specified
Vehicle:
no
Details on test solutions:
The test substance was dissolved in test medium to form a stock solution which was diluted to concentrations of 0.032, 0.1, 0.316, 1 mg/L.
Test organisms (species):
Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
3 d
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
0.14 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
biomass
Remarks on result:
other: CL: 0.02-0.57
Duration:
72 h
Dose descriptor:
EC10
Effect conc.:
0.03 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
biomass
Remarks on result:
other: CL: 0-0.09
Duration:
72 h
Dose descriptor:
EC90
Effect conc.:
0.53 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
biomass
Remarks on result:
other: CL: 0.21-1150
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
0.21 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Duration:
72 h
Dose descriptor:
EC10
Effect conc.:
0.02 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Conclusions:
An algal growth inhibition test was performed employing four test concentrations between 0.032 mg/L and 1 mg/L. Based on biomass and growth rate, EC50 values of 0.14 mg/L and 0.21 mg/L were determined, respectively.
Executive summary:

To investigate potential harmful effects of the test item on aquatic algae or cyanobacteria, an algal growth inhibition test was performed. The test was performed with four test concentrations between 0.032 mg/L and 1 mg/L. With regard to biomass and growth rate, EC50 (72h) values of 0.14 mg/L and 0.21 mg/L were determined, respectively. The ErC10 (72 h) was determined to be 0.02 mg/L.

Description of key information

EC50 growth rate = 0.21 mg/l

Based on the results, the classification in Aquatic Acute and Chronic 1 is required by CLP Regulation.

Key value for chemical safety assessment

EC50 for freshwater algae:
0.21 mg/L

Additional information